Exploring the World of 4-aco-dmt A Comprehensive Guide to Understanding and Purchasing
4-aco-dmt (also known as psilacetin, 4-acetoxy-DMT,O-Acetylpsilocin , or synthetic shrooms) is a semi-synthetic psychoactive drug that has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin. However, some users report that O-acetylpsilocin’s subjective effects differ from those of psilocybin and psilocin. Additionally, some users prefer 4-AcO-DMT to natural psilocybin mushrooms due to feeling fewer adverse side effects such as nausea and heavy body load, which are more frequently reported in experiences involving natural mushrooms. It is the acetylated form of the psilocybin mushroom alkaloid psilocin and is a lower homolog of 4-AcO-MET, 4-AcO-DET, 4-AcO-MiPT and 4-AcO-DiPT.
Understanding 4-AcO-DMT
What is 4-AcO-DMT?
O-Acetylpsilocin (psilacetin) and several other esters of psilocin were patented on January 16, 1963, by Sandoz Ltd via Albert Hofmann & Franz Troxler. Despite this, psilacetin remains a psychedelic compound with a limited history of use. It is theorized to be a prodrug of psilocin, as is psilocybin, which occurs naturally in many species of psychedelic mushrooms. This is because the aromatic acetyl moiety on the 4th position of the indole ring system is subject to deacetylation in acidic conditions such as those found in the stomach. Psilacetin is O-acetylated psilocin, whereas psilocybin is O-phosphorylated
Effects of 4-AcO-DMT
The effects of 4-AcO-DMT are often described as similar to those of psilocybin mushrooms. Users report a range of experiences, including:
Visual and auditory hallucinations
Altered perception of time and space
Increased introspection and self-awareness
Euphoria and emotional release
The intensity and duration of these effects can vary depending on the dosage and
Legal Status Of O-Acetylpsilocin
O-Acetylpsilocin is ambiguously legal for use as a lab reagent or research chemical; however, it is an acetate ester of psilocin, meaning it would be considered akin to a Schedule I Controlled Substance under the Federal Analogue Act if sold for human consumption.
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